PTGIS

Across TCGA cell cohorts, PTGIS RNA expression is significantly associated with the RNA expression of many other genes, with 2,120 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PTGIS-associated genes across cancer lineages are PODN, ARSI, and LRRC32. Each is linked with PTGIS in more than 6 cancer types. Because this analysis shows association rather than direction, both PTGIS-to-partner and partner-to-PTGIS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTGIS versus PODN in SOFT_TISSUE, with a Pearson correlation of 0.42.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGIS→partner) and Y-score (partner→PTGIS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	PODN →	+0.808	+1.795	.004	<.001	2	7
LUNG_NSCLC_LUAD	ARSI →	+1.532	+0.937	<.001	.009	2	5
SKIN	LRRC32 →	+1.139	+1.143	.001	<.001	3	3
OVARY	ADAMTS5 →	+0.933	+1.279	.001	.003	2	4
OESOPHAGUS	FLNC →	+3.105	+1.122	<.001	.003	2	4
BREAST	MDK →	+2.818	+1.670	.002	.002	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,120 associations by consensus.

PTGIS vs PODN — SOFT_TISSUE

Explore this scatter interactively →