PTGIS

Across TCGA cell cohorts, PTGIS RNA expression is significantly associated with the go_rna of many other GO terms, with 1,181 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible PTGIS-associated GO terms across cancer lineages are Response to hydrostatic pressure, Luteinization, and Golgi to plasma membrane protein transport. Each is linked with PTGIS in more than 7 cancer types. Because this analysis shows association rather than direction, both PTGIS-to-partner and partner-to-PTGIS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to hydrostatic pressure grouped by PTGIS-low versus PTGIS-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGIS→partner) and Y-score (partner→PTGIS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Response to hydrostatic pressure →	+0.119	+2.652	<.001	<.001	3	7
OVARY	Luteinization →	+0.990	+1.317	.002	.009	3	7
OVARY	Golgi to plasma membrane protein transport →	+0.086	+1.436	.002	.005	2	8
KIDNEY	Regulation of intrinsic apoptotic signaling pathway →	+0.070	+3.253	.001	<.001	3	6
OVARY	Positive regulation of viral process →	+0.082	+1.442	<.001	.008	2	7
OVARY	Oxidative phosphorylation →	+0.092	+1.522	.001	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,181 associations by consensus.

Response to hydrostatic pressure by PTGIS expression — KIDNEY

Explore this box plot interactively →