PTGIR

Across TCGA patient cohorts, PTGIR mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PTGIR-associated genes across cancer lineages are MPP and pro B-cells. Each is linked with PTGIR in more than 1 cancer types. Because this analysis shows association rather than direction, both PTGIR-to-partner and partner-to-PTGIR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by PTGIR-low versus PTGIR-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGIR→partner) and Y-score (partner→PTGIR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MPP →	+0.017	+3.109	<.001	.043	3	2
SKCM	pro B-cells →	+0.121	+2.832	.005	.034	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MPP by PTGIR expression — LUSC

Explore this box plot interactively →