PTGIR

Across TCGA cell cohorts, PTGIR RNA expression is significantly associated with the go_rna of many other GO terms, with 1,838 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PTGIR-associated GO terms across cancer lineages are Cellular response to chemical stress, Synaptic vesicle endocytosis, and Cellular response to muramyl dipeptide. Each is linked with PTGIR in more than 6 cancer types. Because this analysis shows association rather than direction, both PTGIR-to-partner and partner-to-PTGIR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to chemical stress grouped by PTGIR-low versus PTGIR-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGIR→partner) and Y-score (partner→PTGIR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Cellular response to chemical stress →	+0.053	+1.237	<.001	<.001	3	7
BLOOD_Lymphoma	Synaptic vesicle endocytosis →	+0.068	+1.231	.001	.002	3	7
BLOOD_Lymphoma	Cellular response to muramyl dipeptide →	+0.124	+2.127	<.001	<.001	3	7
LARGE_INTESTINE	Pallium development →	+0.049	+0.057	<.001	.002	3	6
SOFT_TISSUE	Cellular response to epidermal growth factor stimulus →	+0.062	+0.674	.007	.008	2	7
BLOOD_Lymphoma	Microtubule bundle formation →	-0.037	-1.596	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,838 associations by consensus.

Cellular response to chemical stress by PTGIR expression — SOFT_TISSUE

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