PTGFRN

Across TCGA patient cohorts, PTGFRN protein abundance is significantly associated with the RNA expression of many other genes, with 12,278 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTGFRN-associated genes across cancer lineages are COPZ2, FRMD6, and TAGLN. Each is linked with PTGFRN in more than 5 cancer types. Because this analysis shows association rather than direction, both PTGFRN-to-partner and partner-to-PTGFRN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTGFRN versus COPZ2 in OV, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGFRN→partner) and Y-score (partner→PTGFRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COPZ2 →	+1.406	+0.512	<.001	<.001	3	6
BRCA	FRMD6 →	+1.111	+0.425	<.001	<.001	3	5
OV	TAGLN →	+1.092	+0.361	.003	.004	3	5
OV	MYO1E →	+0.777	+0.551	<.001	<.001	3	5
BRCA	HTRA1 →	+1.278	+0.378	<.001	<.001	3	5
UCEC	RNF213 →	-0.738	-0.677	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,278 associations by consensus.

PTGFRN vs COPZ2 — OV

Explore this scatter interactively →