PTGFR

Across TCGA patient cohorts, PTGFR protein abundance is significantly associated with the go_rna of many other GO terms, with 4 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PTGFR-associated GO terms across cancer lineages are Regulation of somatic stem cell population maintenance, Galactolipid metabolic process, and Diencephalon development. Each is linked with PTGFR in more than 1 cancer types. Because this analysis shows association rather than direction, both PTGFR-to-partner and partner-to-PTGFR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of somatic stem cell population maintenance grouped by PTGFR-low versus PTGFR-high in BRCA.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGFR→partner) and Y-score (partner→PTGFR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	Regulation of somatic stem cell population maintenance →	+0.186	+1.374	.003	.002	2	1
BRCA	Galactolipid metabolic process →	+0.069	+1.329	.009	.007	1	1
BRCA	Diencephalon development →	+0.050	+1.321	.002	.007	1	1
BRCA	Mesenchymal to epithelial transition →	+0.183	+1.329	.004	.007	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Regulation of somatic stem cell population maintenance by PTGFR expression — BRCA

Explore this box plot interactively →