PTGFR

Across TCGA cell cohorts, PTGFR RNA expression is significantly associated with the go_rna of many other GO terms, with 3,467 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PTGFR-associated GO terms across cancer lineages are Positive regulation of cell-substrate junction organization, Regulation of cell-matrix adhesion, and Collagen fibril organization. Each is linked with PTGFR in more than 10 cancer types. Because this analysis shows association rather than direction, both PTGFR-to-partner and partner-to-PTGFR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell-substrate junction organization grouped by PTGFR-low versus PTGFR-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGFR→partner) and Y-score (partner→PTGFR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of cell-substrate junction organization →	+0.150	+2.158	<.001	<.001	3	10
BONE	Regulation of cell-matrix adhesion →	+0.150	+2.063	<.001	<.001	2	11
LUNG_NSCLC_LUSC	Collagen fibril organization →	+0.341	+1.541	<.001	<.001	3	10
BONE	Positive regulation of actin filament bundle assembly →	+0.191	+2.151	<.001	<.001	3	10
BONE	Positive regulation of stress fiber assembly →	+0.172	+2.270	<.001	<.001	3	10
BREAST	Negative regulation of plasminogen activation →	+0.430	+1.246	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,467 associations by consensus.

Positive regulation of cell-substrate junction organization by PTGFR expression — BONE

Explore this box plot interactively →