PTGES2

Across TCGA patient cohorts, PTGES2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,506 significant associations in total. COAD shows the largest number of these associations.

The most reproducible PTGES2-associated genes across cancer lineages are TRUB2, NDUFA8, and DOLPP1. Each is linked with PTGES2 in more than 6 cancer types. Because this analysis shows association rather than direction, both PTGES2-to-partner and partner-to-PTGES2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTGES2 versus TRUB2 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGES2→partner) and Y-score (partner→PTGES2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TRUB2 →	+0.626	+0.642	<.001	<.001	3	7
HNSC	NDUFA8 →	+1.199	+0.258	.001	<.001	3	6
LSCC	DOLPP1 →	+0.477	+0.316	<.001	<.001	3	6
OV	HSDL2 →	+0.804	+0.503	.001	.009	3	5
LSCC	NCBP1 →	+0.414	+0.271	<.001	<.001	3	5
LSCC	MRRF →	+0.471	+0.314	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,506 associations by consensus.

PTGES2 vs TRUB2 — OV

Explore this scatter interactively →