PTGER2

Across TCGA patient cohorts, PTGER2 mutation is significantly associated with the RNA expression of many other genes, with 1,659 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTGER2-associated genes across cancer lineages are RNU6-208P, SNORA3C, and PIGW. Each is linked with PTGER2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PTGER2-to-partner and partner-to-PTGER2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-208P grouped by PTGER2-low versus PTGER2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGER2→partner) and Y-score (partner→PTGER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-208P →	+0.490	+4.018	.003	.006	3	3
HNSC	SNORA3C →	+0.625	+3.643	<.001	.001	3	3
UCEC	PIGW →	+0.616	+3.609	.005	.001	3	2
BLCA	RPS29P8 →	+0.265	+2.872	<.001	.004	3	2
SKCM	RNU6-1338P →	+0.169	+3.034	<.001	.008	3	2
UCEC	C18orf25 →	+0.546	+2.711	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,659 associations by consensus.

RNU6-208P by PTGER2 expression — LUAD

Explore this box plot interactively →