PTGER2

Across TCGA cell cohorts, PTGER2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,264 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PTGER2-associated GO terms across cancer lineages are Regulation of dendritic cell antigen processing and presentation, Positive regulation of cell-substrate junction organization, and Collagen metabolic process. Each is linked with PTGER2 in more than 10 cancer types. Because this analysis shows association rather than direction, both PTGER2-to-partner and partner-to-PTGER2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of dendritic cell antigen processing and presentation grouped by PTGER2-low versus PTGER2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGER2→partner) and Y-score (partner→PTGER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of dendritic cell antigen processing and presentation →	+1.639	+1.522	<.001	<.001	3	11
BONE	Positive regulation of cell-substrate junction organization →	+0.138	+1.475	<.001	<.001	3	9
BONE	Collagen metabolic process →	+0.205	+1.528	<.001	<.001	3	9
BONE	Regulation of plasminogen activation →	+0.233	+1.246	<.001	.004	3	9
BONE	Substrate adhesion-dependent cell spreading →	+0.153	+1.486	<.001	<.001	3	9
BONE	Positive regulation of stress fiber assembly →	+0.163	+1.512	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,264 associations by consensus.

Regulation of dendritic cell antigen processing and presentation by PTGER2 expression — BONE

Explore this box plot interactively →