PTGER2

Across TCGA cell cohorts, PTGER2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PTGER2-associated genes across cancer lineages are DSCAM, MC5R, and CLEC5A. Each is linked with PTGER2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTGER2-to-partner and partner-to-PTGER2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DSCAM grouped by PTGER2-low versus PTGER2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGER2→partner) and Y-score (partner→PTGER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DSCAM →	+0.413	+4.165	.004	.001	3	1
BLOOD_Lymphoma	MC5R →	+0.377	+4.165	<.001	.001	3	1
BLOOD_Lymphoma	CLEC5A →	+0.050	+4.142	<.001	.003	3	1
BLOOD_Lymphoma	TPTE →	+0.764	+4.222	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

DSCAM by PTGER2 expression — BLOOD_Lymphoma

Explore this box plot interactively →