PTGER1

Across TCGA cell cohorts, PTGER1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PTGER1-associated genes across cancer lineages are CPXCR1, MAGEB6, and LCE1E. Each is linked with PTGER1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTGER1-to-partner and partner-to-PTGER1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CPXCR1 grouped by PTGER1-low versus PTGER1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGER1→partner) and Y-score (partner→PTGER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CPXCR1 →	+0.079	+3.971	<.001	.002	3	1
BLOOD_Leukemia	MAGEB6 →	+0.244	+4.300	<.001	.001	3	1
BLOOD_Leukemia	LCE1E →	+0.532	+4.359	<.001	<.001	3	1
BLOOD_Leukemia	MYOCD →	+0.914	+3.523	<.001	.003	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CPXCR1 by PTGER1 expression — BLOOD_Leukemia

Explore this box plot interactively →