PTGDR2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PTGDR2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. COAD shows the largest number of these associations.

The most reproducible PTGDR2-associated genes across cancer lineages are Pericytes and Preadipocytes. Each is linked with PTGDR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTGDR2-to-partner and partner-to-PTGDR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pericytes grouped by PTGDR2-low versus PTGDR2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTGDR2→partner) and Y-score (partner→PTGDR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPericytes →+0.151+4.541<.001.01731
COADPreadipocytes →+0.136+4.169<.001.02731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Pericytes by PTGDR2 expression — COAD

Box plot of Pericytes in PTGDR2-low vs PTGDR2-high samples in COAD.

Explore this box plot interactively →

Exploration