PTF1A

Across TCGA patient cohorts, PTF1A RNA expression is significantly associated with the RNA expression of many other genes, with 7,317 significant associations in total. THYM shows the largest number of these associations.

The most reproducible PTF1A-associated genes across cancer lineages are BRSK2, KIF1A, and TMEM151B. Each is linked with PTF1A in more than 12 cancer types. Because this analysis shows association rather than direction, both PTF1A-to-partner and partner-to-PTF1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTF1A versus BRSK2 in TGCT, with a Pearson correlation of 0.39.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTF1A→partner) and Y-score (partner→PTF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	BRSK2 →	+1.213	+0.331	<.001	<.001	3	13
LUSC	KIF1A →	+1.595	+0.132	<.001	.001	3	11
LGG	TMEM151B →	+1.140	+0.144	<.001	<.001	3	10
GBM	GPR137C →	+0.623	+0.084	<.001	<.001	3	10
LUSC	MYEF2 →	+0.679	+0.170	<.001	.002	3	10
COAD	GNG4 →	+1.575	+0.463	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,317 associations by consensus.

PTF1A vs BRSK2 — TGCT

Explore this scatter interactively →