PTF1A

Across TCGA patient cohorts, PTF1A mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTF1A-associated genes across cancer lineages are Monocytes and Adipocytes. Each is linked with PTF1A in more than 1 cancer types. Because this analysis shows association rather than direction, both PTF1A-to-partner and partner-to-PTF1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by PTF1A-low versus PTF1A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTF1A→partner) and Y-score (partner→PTF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Monocytes →	+0.009	+4.810	<.001	.043	3	1
UCEC	Adipocytes →	+0.034	+2.729	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Monocytes by PTF1A expression — SKCM

Explore this box plot interactively →