PTDSS1

Across TCGA patient cohorts, PTDSS1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,618 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTDSS1-associated genes across cancer lineages are ZNF706, AZIN1, and PABPC1. Each is linked with PTDSS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PTDSS1-to-partner and partner-to-PTDSS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTDSS1 versus ZNF706 in LSCC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTDSS1→partner) and Y-score (partner→PTDSS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZNF706 →	+0.506	+0.538	<.001	<.001	3	6
OV	AZIN1 →	+0.635	+0.447	<.001	.001	3	6
HNSC	PABPC1 →	+0.929	+0.435	<.001	<.001	3	6
OV	DERL1 →	+0.477	+0.367	.003	.006	3	4
OV	MTDH →	+0.487	+0.404	.009	.003	3	4
COAD	MTERF3 →	+0.626	+0.412	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,618 associations by consensus.

PTDSS1 vs ZNF706 — LSCC

Explore this scatter interactively →