PTCSC3

Across TCGA patient cohorts, PTCSC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,370 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PTCSC3-associated proteins across cancer lineages are NRBF2, ZNF219_S114, and CKAP4_S26. Each is linked with PTCSC3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PTCSC3-to-partner and partner-to-PTCSC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTCSC3 versus NRBF2 in CCRCC, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCSC3→partner) and Y-score (partner→PTCSC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NRBF2 →	-0.393	-1.135	<.001	<.001	3	4
HNSC	ZNF219_S114 →	+0.669	+0.402	<.001	<.001	3	4
CCRCC	CKAP4_S26 →	-0.759	-0.881	<.001	.003	3	4
CCRCC	DDAH1 →	+0.534	+0.861	<.001	<.001	3	4
CCRCC	EIF3M →	-0.188	-0.771	<.001	<.001	3	4
GBM	EPM2AIP1 →	+0.276	+1.077	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,370 associations by consensus.

PTCSC3 vs NRBF2 — CCRCC

Explore this scatter interactively →