PTCSC2

Across TCGA patient cohorts, PTCSC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,890 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTCSC2-associated proteins across cancer lineages are SPIN1_S199, C8orf33, and WDR18. Each is linked with PTCSC2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PTCSC2-to-partner and partner-to-PTCSC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTCSC2 versus SPIN1_S199 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCSC2→partner) and Y-score (partner→PTCSC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPIN1_S199 →	+0.396	+1.250	.001	<.001	3	4
HNSC	C8orf33 →	-0.269	-0.715	.003	.009	3	3
LSCC	WDR18 →	+0.281	+1.089	<.001	<.001	3	3
GBM	WIZ →	+0.267	+0.376	.006	.002	3	3
LSCC	WNK2_S1862 →	+1.164	+1.266	<.001	<.001	3	3
HNSC	XAB2 →	+0.179	+1.147	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,890 associations by consensus.

PTCSC2 vs SPIN1_S199 — LSCC

Explore this scatter interactively →