PTCRA

Across TCGA patient cohorts, PTCRA mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTCRA-associated genes across cancer lineages are lymphatic Endothelial cells, Neutrophils, and Endothelial cells. Each is linked with PTCRA in more than 1 cancer types. Because this analysis shows association rather than direction, both PTCRA-to-partner and partner-to-PTCRA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, lymphatic Endothelial cells grouped by PTCRA-low versus PTCRA-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCRA→partner) and Y-score (partner→PTCRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	lymphatic Endothelial cells →	-0.024	-3.138	.045	.019	3	1
UCEC	Neutrophils →	+0.015	+1.681	.001	.049	3	1
UCEC	Endothelial cells →	-0.042	-3.416	.028	.005	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

lymphatic Endothelial cells by PTCRA expression — UCEC

Explore this box plot interactively →