PTCHD3

Across TCGA cell cohorts, PTCHD3 RNA expression is significantly associated with the RNA expression of many other genes, with 932 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PTCHD3-associated genes across cancer lineages are LORICRIN, PRAMEF20, and GK2. Each is linked with PTCHD3 in more than 3 cancer types. Because this analysis shows association rather than direction, both PTCHD3-to-partner and partner-to-PTCHD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTCHD3 versus LORICRIN in LARGE_INTESTINE, with a Pearson correlation of 0.96.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCHD3→partner) and Y-score (partner→PTCHD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LORICRIN →	+0.223	+0.024	<.001	<.001	3	4
LUNG_NSCLC_LUSC	PRAMEF20 →	+0.150	+0.054	.002	<.001	3	4
LUNG_NSCLC_LUSC	GK2 →	+0.073	+0.054	.001	<.001	3	3
CNS	RD3L →	+0.146	+0.251	<.001	<.001	3	3
BREAST	PRAMEF8 →	+0.292	+0.310	<.001	<.001	3	3
BREAST	PRAMEF7 →	+0.116	+0.211	.002	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 932 associations by consensus.

PTCHD3 vs LORICRIN — LARGE_INTESTINE

Explore this scatter interactively →