PTCHD1

Across TCGA patient cohorts, PTCHD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,183 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PTCHD1-associated proteins across cancer lineages are PRPH, SMTN, and CTNNAL1_S538. Each is linked with PTCHD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PTCHD1-to-partner and partner-to-PTCHD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTCHD1 versus PRPH in COAD, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCHD1→partner) and Y-score (partner→PTCHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PRPH →	+1.021	+0.326	<.001	<.001	3	4
COAD	SMTN →	+0.810	+0.246	<.001	.006	3	4
LSCC	CTNNAL1_S538 →	+0.990	+0.669	<.001	.001	3	4
BRCA	DAPK3 →	+0.447	+0.908	<.001	<.001	3	4
UCEC	ACTN4 →	+0.355	+0.758	<.001	.006	3	4
UCEC	LAMA4 →	+0.791	+0.961	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,183 associations by consensus.

PTCHD1 vs PRPH — COAD

Explore this scatter interactively →