PTCH2

Across TCGA patient cohorts, PTCH2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,163 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PTCH2-associated proteins across cancer lineages are CNRIP1, KANK2, and SORBS1. Each is linked with PTCH2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PTCH2-to-partner and partner-to-PTCH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTCH2 versus CNRIP1 in BRCA, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCH2→partner) and Y-score (partner→PTCH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CNRIP1 →	+0.651	+0.692	<.001	<.001	3	6
BRCA	KANK2 →	+0.559	+0.647	<.001	<.001	3	5
UCEC	SORBS1 →	+0.835	+0.795	<.001	.001	3	5
UCEC	EFEMP2 →	+0.550	+0.599	<.001	.003	3	5
HNSC	EIF4G1 →	-0.262	-0.517	<.001	.001	2	6
UCEC	MAP1B →	+0.575	+0.522	.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,163 associations by consensus.

PTCH2 vs CNRIP1 — BRCA

Explore this scatter interactively →