PTCD3

Across TCGA patient cohorts, PTCD3 protein abundance is significantly associated with the RNA expression of many other genes, with 17,554 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTCD3-associated genes across cancer lineages are ANTXR2, ZEB2, and PMP22. Each is linked with PTCD3 in more than 7 cancer types. Because this analysis shows association rather than direction, both PTCD3-to-partner and partner-to-PTCD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTCD3 versus ANTXR2 in UCEC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCD3→partner) and Y-score (partner→PTCD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ANTXR2 →	-0.904	-0.314	<.001	<.001	3	8
UCEC	ZEB2 →	-0.673	-0.241	.001	<.001	3	8
BRCA	PMP22 →	-0.827	-0.253	<.001	<.001	3	7
UCEC	CNRIP1 →	-0.883	-0.349	<.001	<.001	3	7
HNSC	SSPN →	-0.735	-0.186	<.001	<.001	3	7
OV	TGFB1I1 →	-0.913	-0.333	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,554 associations by consensus.

PTCD3 vs ANTXR2 — UCEC

Explore this scatter interactively →