PTCD3

Across TCGA cell cohorts, PTCD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,520 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PTCD3-associated GO terms across cancer lineages are Regulation of DNA repair, Double-strand break repair, and Mitochondrial RNA metabolic process. Each is linked with PTCD3 in more than 14 cancer types. Because this analysis shows association rather than direction, both PTCD3-to-partner and partner-to-PTCD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by PTCD3-low versus PTCD3-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCD3→partner) and Y-score (partner→PTCD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of DNA repair →	+0.058	+0.933	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.061	+1.038	<.001	<.001	3	15
CNS	Mitochondrial RNA metabolic process →	+0.072	+0.830	<.001	<.001	3	15
BLOOD_Myeloma	DNA-templated DNA replication →	+0.114	+0.716	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via homologous recombination →	+0.077	+1.385	<.001	<.001	3	14
BREAST	Regulation of G2/M transition of mitotic cell cycle →	+0.075	+0.808	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,520 associations by consensus.

Regulation of DNA repair by PTCD3 expression — LARGE_INTESTINE

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