PTCD3

Across TCGA cell cohorts, PTCD3 mutation is significantly associated with the RNA expression of many other genes, with 541 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PTCD3-associated genes across cancer lineages are ANKRD60, H2BC1, and H2AC1. Each is linked with PTCD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTCD3-to-partner and partner-to-PTCD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD60 grouped by PTCD3-low versus PTCD3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCD3→partner) and Y-score (partner→PTCD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	ANKRD60 →	+0.012	+4.392	<.001	.004	3	1
SOFT_TISSUE	H2BC1 →	+0.260	+4.392	<.001	.004	3	1
SOFT_TISSUE	H2AC1 →	+0.115	+4.392	<.001	.004	3	1
SOFT_TISSUE	GKN1 →	+0.140	+3.736	<.001	.008	3	1
SOFT_TISSUE	AMY1B →	+0.015	+5.050	.008	<.001	3	1
SOFT_TISSUE	OR8D1 →	+0.105	+4.295	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 541 associations by consensus.

ANKRD60 by PTCD3 expression — SOFT_TISSUE

Explore this box plot interactively →