PTCD2P2

Across TCGA pan-cancer cohorts, PTCD2P2 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PTCD2P2 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PTCD2P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PTCD2P2 expression acts as an unfavorable survival marker, although some lineages such as LGG and PRAD show a favorable association.

HNSC, KIRP, and THYM are the cancer types where PTCD2P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.282	0.739	<.001	72	view →
KIRP	DFS	Tertile	II,III,IV	0.441	0.798	.008	42	view →
THYM	DFS	Tertile	II,III,IV	0.258	0.788	.006	39	view →
TGCT	DFS	Tertile	II,III,IV	0.518	0.996	<.001	36	view →
STAD	OS	Tertile	II,III,IV	0.230	0.610	.010	36	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
LIHC	DFS	Tertile	II,III,IV	0.135	0.482	.002	27	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
LGG	OS	Tertile	All	0.673	0.349	.007	15	view →
READ	DFS	Tertile	III,IV	0.306	0.603	.007	15	view →
KIRC	OS	Quartile	All	0.819	0.898	.006	13	view →
LUSC	OS	Tertile	All	0.669	0.791	.008	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

PTCD2P2–HNSC (OS)

Open the HNSC breakdown →