PTCD2

Across TCGA patient cohorts, PTCD2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,281 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PTCD2-associated genes across cancer lineages are FBLN5, HSPA4, and TAF5LP1. Each is linked with PTCD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PTCD2-to-partner and partner-to-PTCD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTCD2 versus FBLN5 in BRCA, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCD2→partner) and Y-score (partner→PTCD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FBLN5 →	-1.180	-0.565	<.001	<.001	3	3
LUAD	HSPA4 →	+0.579	+0.379	<.001	.002	3	3
HNSC	TAF5LP1 →	-1.047	-0.485	.001	<.001	3	3
HNSC	CELF2 →	-1.151	-0.739	.005	<.001	3	3
HNSC	SH3KBP1 →	-0.648	-0.417	.002	.003	3	3
HNSC	SYNE3 →	-0.660	-0.438	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,281 associations by consensus.

PTCD2 vs FBLN5 — BRCA

Explore this scatter interactively →