PTCD2

Across TCGA cell cohorts, PTCD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,508 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PTCD2-associated GO terms across cancer lineages are Double-strand break repair via nonhomologous end joining, Protein localization to cilium, and Nucleotide-excision repair. Each is linked with PTCD2 in more than 14 cancer types. Because this analysis shows association rather than direction, both PTCD2-to-partner and partner-to-PTCD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair via nonhomologous end joining grouped by PTCD2-low versus PTCD2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCD2→partner) and Y-score (partner→PTCD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via nonhomologous end joining →	+0.078	+1.077	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Protein localization to cilium →	+0.052	+0.960	.003	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Nucleotide-excision repair →	+0.076	+0.955	<.001	<.001	3	14
PANCREAS	Positive regulation of rRNA processing →	+0.130	+0.843	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of mitochondrial gene expression →	+0.070	+0.860	.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mismatch repair →	+0.108	+0.970	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,508 associations by consensus.

Double-strand break repair via nonhomologous end joining by PTCD2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →