PTCD2

Across TCGA cell cohorts, PTCD2 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PTCD2-associated genes across cancer lineages are C6orf118, TAAR5, and DEFA4. Each is linked with PTCD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTCD2-to-partner and partner-to-PTCD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by PTCD2-low versus PTCD2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCD2→partner) and Y-score (partner→PTCD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.104	+3.793	.005	.007	3	1
LARGE_INTESTINE	TAAR5 →	+0.014	+4.437	<.001	.004	3	1
LARGE_INTESTINE	DEFA4 →	+0.032	+4.437	<.001	.004	3	1
LARGE_INTESTINE	TBC1D21 →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	ACSM6 →	+0.027	+4.169	<.001	.007	3	1
LARGE_INTESTINE	C12orf40 →	+0.009	+3.684	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

C6orf118 by PTCD2 expression — LARGE_INTESTINE

Explore this box plot interactively →