PTCD1

Across TCGA patient cohorts, PTCD1 protein abundance is significantly associated with the RNA expression of many other genes, with 225 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PTCD1-associated genes across cancer lineages are SPEF1, UNC93B1, and MRPS30. Each is linked with PTCD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTCD1-to-partner and partner-to-PTCD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTCD1 versus SPEF1 in BRCA, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCD1→partner) and Y-score (partner→PTCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SPEF1 →	+1.471	+0.650	<.001	.002	3	1
BRCA	UNC93B1 →	+0.893	+0.460	.003	.005	3	1
BRCA	MRPS30 →	+1.826	+0.521	.005	.004	3	1
BRCA	SLC46A2 →	+0.536	+0.557	<.001	.002	3	1
BRCA	RBCK1 →	+0.584	+0.615	<.001	.008	3	1
BRCA	NINJ1 →	+0.859	+0.680	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 225 associations by consensus.

PTCD1 vs SPEF1 — BRCA

Explore this scatter interactively →