PTCD1

Across TCGA cell cohorts, PTCD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,469 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PTCD1-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Positive regulation of isotype switching to IgG isotypes, and Ribosome assembly. Each is linked with PTCD1 in more than 16 cancer types. Because this analysis shows association rather than direction, both PTCD1-to-partner and partner-to-PTCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by PTCD1-low versus PTCD1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTCD1→partner) and Y-score (partner→PTCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.213	+0.603	<.001	.005	3	17
BLOOD_Lymphoma	Positive regulation of isotype switching to IgG isotypes →	+0.144	+0.873	<.001	<.001	3	17
BONE	Ribosome assembly →	+0.093	+0.672	<.001	<.001	3	13
BONE	Positive regulation of DNA recombination →	+0.086	+0.521	<.001	.001	3	13
BONE	Nucleic acid transport →	+0.116	+0.698	<.001	<.001	3	13
BONE	RNA transport →	+0.116	+0.698	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,469 associations by consensus.

Pre-mRNA catabolic process by PTCD1 expression — BONE

Explore this box plot interactively →