PTBP3

Across TCGA cell cohorts, PTBP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,985 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PTBP3-associated GO terms across cancer lineages are Immunoglobulin heavy chain V-D-J recombination, Organophosphate catabolic process, and Endosomal transport. Each is linked with PTBP3 in more than 12 cancer types. Because this analysis shows association rather than direction, both PTBP3-to-partner and partner-to-PTBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin heavy chain V-D-J recombination grouped by PTBP3-low versus PTBP3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTBP3→partner) and Y-score (partner→PTBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Immunoglobulin heavy chain V-D-J recombination →	+0.165	+0.865	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Organophosphate catabolic process →	-0.071	-1.082	.001	.005	3	13
STOMACH	Endosomal transport →	+0.052	+0.879	<.001	<.001	3	12
LUNG_SCLC	Protein polyubiquitination →	+0.043	+1.033	.003	<.001	3	12
OVARY	Proteasome regulatory particle assembly →	+0.145	+1.024	<.001	<.001	3	11
BREAST	Cell cycle checkpoint signaling →	+0.073	+0.899	.002	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,985 associations by consensus.

Immunoglobulin heavy chain V-D-J recombination by PTBP3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →