PTBP1P

Across TCGA pan-cancer cohorts, PTBP1P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated PTBP1P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PTBP1P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PTBP1P expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

HNSC, SKCM, and STAD are the cancer types where PTBP1P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	0.416	0.203	<.001	141	view →
SKCM	OS	Median	All	0.426	0.242	<.001	101	view →
STAD	DFS	Tertile	II,III,IV	0.405	0.628	<.001	90	view →
KIRC	DFS	Tertile	All	0.728	0.839	<.001	77	view →
LGG	OS	Median	All	0.720	0.888	<.001	53	view →
UVM	DFS	Median	II,III,IV	0.428	0.752	<.001	45	view →
UCS	DFS	Median	IV	0.885	0.440	.015	30	view →
BLCA	OS	Tertile	III,IV	0.491	0.134	.004	28	view →
KIRP	OS	Quartile	All	0.869	0.962	.002	27	view →
THYM	DFS	Median	All	0.820	0.952	.015	15	view →
MESO	DFS	Tertile	III,IV	0.277	0.512	.018	13	view →
THCA	DFS	Quartile	II,III,IV	0.696	0.963	.004	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

PTBP1P–HNSC (DFS)

Open the HNSC breakdown →