Across TCGA patient cohorts, PTAR1 mutation is significantly associated with the RNA expression of many other genes, with 1,644 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTAR1-associated genes across cancer lineages are RNU6-552P, RNU6-1318P, and CLRN2. Each is linked with PTAR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTAR1-to-partner and partner-to-PTAR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTAR1→partner) and Y-score (partner→PTAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-552P →	+0.455	+5.106	<.001	.008	3	2
BLCA	RNU6-1318P →	+0.442	+5.588	<.001	.004	3	2
BLCA	CLRN2 →	+0.081	+5.411	<.001	.005	3	2
BLCA	MIR1273H →	+0.389	+4.973	<.001	.009	3	2
COAD	RNA5SP167 →	+0.514	+4.807	<.001	.004	3	2
COAD	RN7SL763P →	+0.232	+4.807	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,644 associations by consensus.

Exploration

PTAR1 survival (RNA) · tumor vs normal (RNA) · all PTAR1 data types