Across TCGA patient cohorts, PTAR1 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTAR1-associated genes across cancer lineages are JNK2, Akt_pT308, and Rad50. Each is linked with PTAR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTAR1-to-partner and partner-to-PTAR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTAR1→partner) and Y-score (partner→PTAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.287	+3.348	.001	.004	3	2
UCEC	Akt_pT308 →	+0.686	+3.169	.015	.018	3	2
UCEC	Rad50 →	-0.264	-2.000	.015	.032	3	2
UCEC	Fibronectin →	-0.296	-2.312	.046	.034	3	1
UCEC	GSK-3_pS9 →	+0.405	+2.000	.026	.032	3	1
UCEC	GSK-3a-b_pS21_S9 →	+0.516	+3.807	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

PTAR1 survival (RNA) · tumor vs normal (RNA) · all PTAR1 data types