PSTPIP1

Across TCGA pan-cancer cohorts, PSTPIP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated PSTPIP1 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PSTPIP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PSTPIP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

COAD, LUAD, and PDAC are the cancer types where PSTPIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	II,III,IV	0.672	1.000	.016	48	view →
LUAD	DFS	Tertile	All	0.786	0.519	.017	7	view →
PDAC	DFS	Median	IV	0.934	0.250	.024	7	view →
GBM	OS	Quartile	All	0.728	0.903	.007	4	view →
UCEC	OS	Median	II,III,IV	1.000	0.628	.013	4	view →
LSCC	DFS	Quartile	All	0.815	0.369	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

PSTPIP1–COAD (DFS)

Open the COAD breakdown →