PSTPIP1

Across TCGA cell cohorts, PSTPIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,669 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PSTPIP1-associated GO terms across cancer lineages are Specification of animal organ identity, Regulation of bone development, and Negative regulation of interleukin-1 alpha production. Each is linked with PSTPIP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PSTPIP1-to-partner and partner-to-PSTPIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Specification of animal organ identity grouped by PSTPIP1-low versus PSTPIP1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSTPIP1→partner) and Y-score (partner→PSTPIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Specification of animal organ identity →	-1.035	-2.304	<.001	<.001	3	5
LUNG_SCLC	Regulation of bone development →	-0.203	-1.933	<.001	<.001	3	5
BONE	Negative regulation of interleukin-1 alpha production →	+1.030	+0.871	<.001	.002	3	5
KIDNEY	Astrocyte development →	+0.082	+0.102	.005	.001	3	5
LUNG_SCLC	Renal water absorption →	-0.508	-1.269	.006	.001	3	4
LUNG_SCLC	Regulation of postsynaptic cytosolic calcium ion concentration →	+0.764	+1.528	.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,669 associations by consensus.

Specification of animal organ identity by PSTPIP1 expression — BLOOD_Leukemia

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