PSRC1

Across TCGA cell cohorts, PSRC1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PSRC1-associated genes across cancer lineages are BPIFA1, FAM205A, and ASB17. Each is linked with PSRC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSRC1-to-partner and partner-to-PSRC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFA1 grouped by PSRC1-low versus PSRC1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSRC1→partner) and Y-score (partner→PSRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BPIFA1 →	+0.109	+3.103	.005	.004	3	1
LARGE_INTESTINE	FAM205A →	+0.023	+5.029	<.001	<.001	3	1
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	1
LARGE_INTESTINE	SH3GL2 →	+1.469	+3.252	<.001	.009	2	1
LARGE_INTESTINE	TKTL2 →	+0.045	+3.187	<.001	.006	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

BPIFA1 by PSRC1 expression — LARGE_INTESTINE

Explore this box plot interactively →