PSPC1

Across TCGA patient cohorts, PSPC1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,993 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PSPC1-associated genes across cancer lineages are FCGR2A, DSE, and LINC01094. Each is linked with PSPC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PSPC1-to-partner and partner-to-PSPC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSPC1 versus FCGR2A in GBM, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSPC1→partner) and Y-score (partner→PSPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FCGR2A →	-0.899	-0.299	<.001	<.001	3	6
CCRCC	DSE →	-0.572	-0.193	.001	<.001	3	6
GBM	LINC01094 →	-0.705	-0.270	.001	.001	3	6
LSCC	CCDC138 →	+0.605	+0.225	<.001	<.001	3	5
HNSC	RPRD2 →	+0.447	+0.215	.001	<.001	3	5
OV	RAB31 →	-0.953	-0.398	.004	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,993 associations by consensus.

PSPC1 vs FCGR2A — GBM

Explore this scatter interactively →