Across TCGA patient cohorts, PSORS1C3 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSORS1C3-associated genes across cancer lineages are IGKV2OR2-7D, MIR3193, and MIR4298. Each is linked with PSORS1C3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSORS1C3-to-partner and partner-to-PSORS1C3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSORS1C3→partner) and Y-score (partner→PSORS1C3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV2OR2-7D →	+0.120	+4.771	.008	.006	3	1
UCEC	MIR3193 →	+1.055	+4.423	<.001	.006	3	1
UCEC	MIR4298 →	+0.506	+4.621	<.001	.008	3	1
UCEC	RNA5SP205 →	+0.349	+4.852	.002	.006	3	1
UCEC	MIR128-1 →	+0.377	+4.937	.006	.005	3	1
UCEC	IGHD1-26 →	+1.849	+6.069	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

PSORS1C3 survival (RNA) · tumor vs normal (RNA) · all PSORS1C3 data types