PSORS1C2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PSORS1C2 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSORS1C2-associated genes across cancer lineages are Ku80 and c-Met_pY1235. Each is linked with PSORS1C2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSORS1C2-to-partner and partner-to-PSORS1C2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSORS1C2→partner) and Y-score (partner→PSORS1C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECKu80 →+0.446+2.820.002.03631
UCECc-Met_pY1235 →+0.113+2.817.013.03631
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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