PSMG3

Across TCGA cell cohorts, PSMG3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,124 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PSMG3-associated GO terms across cancer lineages are Meiotic mismatch repair, rRNA 2'-O-methylation, and Deactivation of mitotic spindle assembly checkpoint. Each is linked with PSMG3 in more than 11 cancer types. Because this analysis shows association rather than direction, both PSMG3-to-partner and partner-to-PSMG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic mismatch repair grouped by PSMG3-low versus PSMG3-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMG3→partner) and Y-score (partner→PSMG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Meiotic mismatch repair →	+0.127	+1.226	<.001	<.001	3	12
LUNG_SCLC	rRNA 2'-O-methylation →	+0.111	+0.525	.001	.002	2	12
CNS	Deactivation of mitotic spindle assembly checkpoint →	+0.162	+0.626	<.001	<.001	3	8
BONE	Positive regulation of isotype switching to IgG isotypes →	+0.128	+0.673	.002	.002	3	8
OVARY	Positive regulation of triglyceride catabolic process →	+0.128	+0.531	.003	.001	3	8
SKIN	Maintenance of unfolded protein →	+0.115	+0.802	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,124 associations by consensus.

Meiotic mismatch repair by PSMG3 expression — BLOOD_Myeloma

Explore this box plot interactively →