Across TCGA pan-cancer cohorts, PSMG1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PSMG1 data layer compared with 26 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher PSMG1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PSMG1 expression acts as an unfavorable survival marker.

BLCA, HNSC, and LIHC are the cancer types where PSMG1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.117	0.720	<.001	36	view →
HNSC	OS	Median	II,III,IV	0.069	0.757	<.001	12	view →
LIHC	OS	Median	II,III,IV	0.239	0.715	.035	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: PSMG1 tumor-vs-normal RNA expression · all PSMG1 data types