Across TCGA cell cohorts, PSMG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,910 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PSMG1-associated GO terms across cancer lineages are DNA replication initiation, CENP-A containing chromatin assembly, and Negative regulation of chromosome segregation. Each is linked with PSMG1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PSMG1-to-partner and partner-to-PSMG1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMG1→partner) and Y-score (partner→PSMG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	DNA replication initiation →	+0.186	+0.916	<.001	<.001	3	15
LIVER	CENP-A containing chromatin assembly →	+0.148	+0.797	<.001	<.001	3	15
KIDNEY	Negative regulation of chromosome segregation →	+0.131	+1.241	<.001	<.001	3	14
CNS	Negative regulation of spindle checkpoint →	+0.185	+0.577	<.001	<.001	3	13
KIDNEY	Regulation of mitotic sister chromatid separation →	+0.169	+1.486	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of chromosome condensation →	+0.191	+0.919	.002	.004	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,910 associations by consensus.

Exploration

PSMG1 survival (RNA) · tumor vs normal (RNA) · all PSMG1 data types