PSMF1

Across TCGA pan-cancer cohorts, PSMF1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PSMF1 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PSMF1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PSMF1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where PSMF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	0.970	0.410	.003	11	view →
LUAD	DFS	Median	III,IV	0.289	0.763	.005	6	view →
LSCC	OS	Quartile	III,IV	0.588	0.912	.033	4	view →
PDAC	OS	Tertile	IV	0.231	0.934	.024	3	view →
HNSC	DFS	Median	IV	0.775	0.572	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PSMF1–CCRCC (DFS)

Open the CCRCC breakdown →