PSMF1

Across TCGA cell cohorts, PSMF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,828 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PSMF1-associated GO terms across cancer lineages are Positive regulation of protein localization to endoplasmic reticulum, Regulation of protein localization to endoplasmic reticulum, and Positive regulation of intracellular transport. Each is linked with PSMF1 in more than 16 cancer types. Because this analysis shows association rather than direction, both PSMF1-to-partner and partner-to-PSMF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to endoplasmic reticulum grouped by PSMF1-low versus PSMF1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PSMF1→partner) and Y-score (partner→PSMF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of protein localization to endoplasmic reticulum →	+0.139	+1.391	<.001	<.001	3	17
STOMACH	Regulation of protein localization to endoplasmic reticulum →	+0.120	+1.024	<.001	<.001	3	16
LARGE_INTESTINE	Positive regulation of intracellular transport →	+0.064	+1.172	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.069	+0.803	<.001	<.001	3	14
BLOOD_Lymphoma	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.110	+1.325	<.001	<.001	3	13
STOMACH	Negative regulation of DNA-templated transcription initiation →	+0.139	+0.752	.007	.006	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,828 associations by consensus.

Positive regulation of protein localization to endoplasmic reticulum by PSMF1 expression — URINARY_TRACT

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