PSME3IP1

Across TCGA pan-cancer cohorts, PSME3IP1 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated PSME3IP1 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PSME3IP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PSME3IP1 expression acts as an unfavorable survival marker, although some lineages such as COAD and LUAD show a favorable association.

COAD, LUAD, and PDAC are the cancer types where PSME3IP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.887	.021	18	view →
LUAD	DFS	Quartile	III,IV	0.877	0.265	.019	13	view →
PDAC	DFS	Quartile	III,IV	0.904	0.317	.017	11	view →
LSCC	DFS	Median	II,III,IV	0.829	0.524	.010	9	view →
UCEC	DFS	Quartile	All	0.965	0.727	.024	8	view →
GBM	DFS	Quartile	All	0.463	0.284	.028	2	view →
CCRCC	DFS	Tertile	All	0.626	0.892	.049	1	view →
HNSC	DFS	Median	III,IV	0.913	0.992	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

PSME3IP1–COAD (DFS)

Open the COAD breakdown →