PSME3IP1

Across TCGA patient cohorts, PSME3IP1 mutation is significantly associated with the RNA expression of many other genes, with 1,036 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSME3IP1-associated genes across cancer lineages are RN7SL504P, CRYAA2, and RNU6-546P. Each is linked with PSME3IP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSME3IP1-to-partner and partner-to-PSME3IP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL504P grouped by PSME3IP1-low versus PSME3IP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSME3IP1→partner) and Y-score (partner→PSME3IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL504P →	+0.087	+2.912	.004	.009	3	2
SKCM	CRYAA2 →	+0.297	+5.075	<.001	.001	3	1
BRCA	RNU6-546P →	+0.323	+8.471	<.001	.005	3	1
SKCM	CFL1P8 →	+0.101	+4.500	.008	.005	3	1
SKCM	EI24P1 →	+0.056	+4.913	<.001	.002	3	1
SKCM	RPL30P12 →	+0.133	+4.241	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,036 associations by consensus.

RN7SL504P by PSME3IP1 expression — UCEC

Explore this box plot interactively →