PSME3IP1

Across TCGA patient cohorts, PSME3IP1 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSME3IP1-associated genes across cancer lineages are PCNA, Rab11, and Annexin-1. Each is linked with PSME3IP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PSME3IP1-to-partner and partner-to-PSME3IP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by PSME3IP1-low versus PSME3IP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSME3IP1→partner) and Y-score (partner→PSME3IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.285	+3.000	.006	.036	3	1
UCEC	Rab11 →	-0.197	-3.584	.004	.002	3	1
UCEC	Annexin-1 →	+0.727	+2.459	.004	.020	3	1
UCEC	STAT3_pY705 →	-0.409	-2.999	.001	.035	3	1
UCEC	cIAP →	+0.163	+3.179	.013	.010	3	1
UCEC	4E-BP1 →	+0.348	+2.459	.007	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

PCNA by PSME3IP1 expression — UCEC

Explore this box plot interactively →