PSME3

Across TCGA patient cohorts, PSME3 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,265 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PSME3-associated proteins across cancer lineages are DNAJC7, DHX8, and SMC2. Each is linked with PSME3 in more than 6 cancer types. Because this analysis shows association rather than direction, both PSME3-to-partner and partner-to-PSME3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PSME3 versus DNAJC7 in LSCC, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PSME3→partner) and Y-score (partner→PSME3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DNAJC7 →	+0.339	+0.587	<.001	<.001	3	7
LSCC	DHX8 →	+0.377	+0.759	<.001	<.001	3	7
LSCC	SMC2 →	+0.558	+0.577	<.001	<.001	3	6
LUAD	PPP1R10 →	+0.259	+0.453	<.001	<.001	3	6
LUAD	DDX21 →	+0.622	+0.454	<.001	<.001	3	6
GBM	CTNNBL1 →	+0.291	+0.319	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,265 associations by consensus.

PSME3 vs DNAJC7 — LSCC

Explore this scatter interactively →